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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C6orf165
All Species:
20
Human Site:
Y228
Identified Species:
40
UniProt:
Q8IYR0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYR0
NP_849145.1
622
71193
Y228
A
T
M
Q
H
I
D
Y
Q
L
E
T
A
R
S
Chimpanzee
Pan troglodytes
XP_001154333
622
71118
Y228
A
T
M
Q
H
I
D
Y
Q
L
E
T
A
R
S
Rhesus Macaque
Macaca mulatta
XP_001089007
675
76753
A294
E
G
I
D
D
L
P
A
V
L
H
V
A
I
P
Dog
Lupus familis
XP_532227
634
72396
S240
A
T
T
Q
H
I
D
S
Q
I
Q
I
A
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6PE87
622
70927
S228
T
T
T
Q
H
I
D
S
Q
L
Q
I
A
Q
D
Rat
Rattus norvegicus
A1A5Q4
622
70816
S228
A
T
T
H
H
I
D
S
Q
L
Q
I
A
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513345
621
70882
S228
L
T
T
Q
H
L
D
S
E
L
Q
A
S
Q
N
Chicken
Gallus gallus
XP_419848
621
70424
D228
S
A
T
Q
S
I
E
D
H
L
N
A
C
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2RV06
624
69885
R228
G
V
V
S
D
L
E
R
E
L
A
S
C
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611498
576
66763
E208
D
G
P
D
G
D
R
E
N
V
R
S
V
V
D
Honey Bee
Apis mellifera
XP_394079
485
56983
G117
D
C
Q
R
G
G
E
G
I
D
D
L
P
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780272
623
70581
T228
A
T
T
Q
N
V
D
T
A
I
Q
R
A
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
86.8
84.8
N.A.
79.9
80.5
N.A.
71.3
58
N.A.
48.4
N.A.
20.7
29.1
N.A.
58.4
Protein Similarity:
100
99.8
87.1
90.8
N.A.
90
90.6
N.A.
85.3
76.6
N.A.
67.1
N.A.
40.1
48.5
N.A.
77.2
P-Site Identity:
100
100
13.3
53.3
N.A.
53.3
53.3
N.A.
33.3
26.6
N.A.
6.6
N.A.
0
0
N.A.
33.3
P-Site Similarity:
100
100
26.6
73.3
N.A.
66.6
66.6
N.A.
73.3
40
N.A.
40
N.A.
13.3
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
0
0
0
0
0
9
9
0
9
17
59
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
17
9
0
% C
% Asp:
17
0
0
17
17
9
59
9
0
9
9
0
0
0
25
% D
% Glu:
9
0
0
0
0
0
25
9
17
0
17
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
0
0
17
9
0
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
9
50
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
9
0
0
50
0
0
9
17
0
25
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
25
0
0
0
67
0
9
0
0
0
% L
% Met:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
9
% N
% Pro:
0
0
9
0
0
0
9
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
9
59
0
0
0
0
42
0
42
0
0
34
0
% Q
% Arg:
0
0
0
9
0
0
9
9
0
0
9
9
0
25
9
% R
% Ser:
9
0
0
9
9
0
0
34
0
0
0
17
9
0
17
% S
% Thr:
9
59
50
0
0
0
0
9
0
0
0
17
0
0
0
% T
% Val:
0
9
9
0
0
9
0
0
9
9
0
9
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _